PINPOINT GI System
PINPOINT Distinguishes Between Healthy and Unhealthy Tissue
Novadaq is developing the PINPOINT GI* System for autofluorescence colonoscopy to improve the detection and localization of flat and polypoid cancerous tissue in the colon. Autofluorescence (AF) occurs when epithelial tissue is illuminated with blue light. When illuminated, naturally occurring fluorophores in the tissue emit light in wavelengths of red and green. Healthy tissue emits green light or “fluorescence”, but as tissue progresses from healthy to abnormal, the intensity of the green light diminishes. During colonoscopy, PINPOINT GI enables physicians to visualize the contrast between healthy and unhealthy tissue.
PINPOINT GI is an extension of Novadaq's autofluorescence core techology. PINPOINT is FDA approved for use in bronchoscopy. Prior to approval, PINPOINT demonstrated a 325% per-lesion improvement in the detection of early lung cancer and a 250% per-patient improvement compared to white light alone in an international multi-centre clinical trial. Independent studies of PINPOINT GI have also demonstrated significant improvements in the detection of rates of cancerous lesions in the colon.
PINPOINT may assist physicians performing colonoscopy by more effectively:
- Identifying polypoid and non-polypoid lesions in the colon
- Delineating cancerous margins
- Confirming the presence/absence of synchronous lesions
The PINPOINT GI System consists of an endoscopic light source and high definition video camera that operates in real-time in two imaging modes: conventional white light imaging mode and fluorescence imaging mode. PINPOINT GI is designed for use with conventional video endoscopes. Real-time images produced by PINPOINT GI can be displayed on a color video monitor, such as those normally available for endoscopy applications.
* PINPOINT GI is not yet FDA cleared or approved for sale in the United States
NOVADAQ®, SPY®, SPY PAQ®, NOVADRAPE®, PINPOINT®, VICTORIA® are registered trademarks of Novadaq Technologies Inc.